Inhibition of Fe²⁺-Induced Lipid Peroxidation in Egg Yolk Lipoproteins by Metallothionein

A. N. Koterov¹

¹Russian State Research Center, Institute of Biophysics, ul. Zhivopisnaya 46, Moscow, 123182, Russia; fax: (7-095) 190-35-90; E-mail: ibkoguc@alara.msk.su

Submitted September 1, 1995; revision submitted July 22, 1996.

Rat hepatic apometallothionein and to a lesser extent Zn-metallothionein inhibit Fe²⁺-dependent lipid peroxidation (LPO) in suspensions of egg yolk lipoproteins. ZnCl₂ or its combination with cysteine at corresponding concentrations activate LPO.

KEY WORDS: metallothionein, lipid peroxidation, lipoproteins.

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