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Mitochondrial Creatine Kinase: Properties and Function

T. Yu. Lipskaya

Department of Biochemistry, School of Biology, Lomonosov Moscow State University, Moscow, 119899 Russia; fax: (095) 939-3955

Received April 27, 2001; Revision received July 6, 2001
This review describes properties of mitochondrial creatine kinase from heart and skeletal muscle studied in the author's group at the Department of Biochemistry of Moscow State University. The results are compared to the data in the literature. The author's point of view on the physiological role of mitochondrial creatine kinase is presented.
KEY WORDS: mitochondrial creatine kinase, binding to membranes, oligomeric forms, physicochemical properties, physiological role