REVIEW: Noncoding RNAs

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J. A. Makarova and D. A. Kramerov^*

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, 119991 Moscow, Russia; fax: (495) 135-1405; E-mail: makarova@eimb.ru; kramerov@eimb.ru

^* To whom correspondence should be addressed.

Received June 5, 2007

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There has been substantial progress in studies on non-protein-coding RNAs (ncRNAs) during the last decade. Due to the development of new experimental approaches, a wide variety of such molecules have been found. This review considers the major groups of eukaryotic ncRNAs successfully studied in recent years. In particular, snoRNAs and scaRNAs involved in RNA modification and also miRNAs, siRNAs, tasiRNAs, and piRNAs responsible for RNA silencing are discussed. The transcripts of SINEs and SINE-like genes are considered separately.

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KEY WORDS: ncRNA, SRA RNA, 7SK RNA, NRSE RNA, snoRNA, scaRNA, miRNA, tasiRNA, piRNA, BC1 RNA, BC200 RNA, 4.5S RNA

DOI: 10.1134/S0006297907110016

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