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REVIEW: The Mitochondrial Genome. The Nucleoid

A. A. Kolesnikov

Lomonosov Moscow State University, Faculty of Biology, 119991 Moscow, Russia; E-mail: aak330@yandex.ru

Received May 30, 2016; Revision received July 1, 2016
Mitochondrial DNA (mtDNA) in cells is organized in nucleoids containing DNA and various proteins. This review discusses questions of organization and structural dynamics of nucleoids as well as their protein components. The structures of mt-nucleoid from different organisms are compared. The currently accepted model of nucleoid organization is described and questions needing answers for better understanding of the fine mechanisms of the mitochondrial genetic apparatus functioning are discussed.
KEY WORDS: mitochondrial nucleoid, mitochondrial genome

DOI: 10.1134/S0006297916100047