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Overcoming Antibiotic Resistance in Microorganisms: Molecular Mechanisms


A. G. Gabibov1,2, O. A. Dontsova1,2,3, and A. M. Egorov2,a*

1Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia

2Faculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia

3Center of Life Sciences, Skolkovo Institute of Science and Technology, 143028 Skolkovo, Russia

* To whom correspondence should be addressed.

Received October 12, 2020; Revised October 12, 2020; Accepted October 12, 2020
This issue of the Biochemistry (Moscow) journal presents reviews and experimental articles on the new strategies for solving the problem of antibiotic resistance and on the search for novel antimicrobial preparations using the methods of molecular biology, genetics, and nanotechnology. A wide variety of scientific approaches and successful (as a rule) research results give hope for overcoming microbial antibiotic resistance in the fight against infectious diseases.
KEY WORDS: antimicrobial drugs, resistance, recombinant technologies, new inhibitors

DOI: 10.1134/S0006297920110012