2Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia
* To whom correspondence should be addressed.
Received July 22, 2022; Revised August 18, 2022; Accepted August 19, 2022
The review is devoted to the patterns of evolution of α- and β-globin gene domains. A hypothesis is presented according to which segregation of the ancestral cluster of α/β-globin genes in Amniota occurred due to the performance by α-globins and β-globins of non-canonical functions not related to oxygen transport.
KEY WORDS: evolution of α- and β-globin genes, regulation of transcription, non-canonical functions of α- and β-globins